https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:49277 Wed 10 May 2023 12:24:12 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:47837 n = 330), annual transition probabilities were obtained between no/mild (Expanded Disability Status Scale (EDSS) levels 0-3.5), moderate (EDSS 4-6.0) and severe (EDSS 6.5-9.5) disability. Results: From no/mild disability, 6.4% (95% confidence interval (CI): 4.7-8.4) and 0.1% (0.0-0.2) progressed to moderate and severe disability annually, respectively. From moderate disability, 6.9% (1.0-11.4) improved (to no/mild state) and 2.6% (1.1-4.5) worsened. From severe disability, 0.0% improved to moderate and no/mild disability. Male sex, age at onset, longer disease duration, not using immunotherapies greater than 3 months and a history of relapse were related to higher probabilities of worsening. Conclusion: We have estimated probabilities of changing disability levels in Australians with RRMS. Probabilities differed between various subgroups, but due to small sample sizes, results should be interpreted with caution. Our findings will be helpful in predicting long-term disease outcomes and in health economic evaluations of MS.]]> Wed 01 Feb 2023 15:34:54 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44251 Tue 11 Oct 2022 12:28:43 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:40549 Thu 14 Jul 2022 14:49:19 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:37424 Thu 12 Nov 2020 18:13:51 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:38459 Thu 08 Jun 2023 15:45:05 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:50071 Fri 30 Jun 2023 11:20:29 AEST ]]>